Toxoplasma Gondii. The Model Apicomplexan - Perspectives and Methods

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Unsporulated oocysts are shed in the faeces of cats and meiosis gives rise to haploid sporozoites within the oocysts. These, now infectious, sporulated oocysts contaminate the environment as a source of infection for people and their livestock. RNA-Seq analysis of cat enteric stages of T.

Toxoplasma Gondii - Louis M Weiss - Bok () | Bokus

Inoculation of cats with this engineered parasite strain totally prevented oocyst excretion following infection with wild-type T. Toxoplasma gondii is a zoonotic, apicomplexan parasite that belongs to the subclass Coccidia. On one hand, this protozoan is an important cause of abortion in sheep and, thereby, causes considerable economic losses 1 , 2. On the other hand, the global prevalence of T. Although for most infected people the disease is asymptomatic, a first infection during pregnancy can lead to congenital toxoplasmosis, which may cause abortion or have serious effects for the new-born — effects that may persist for life for example, mental retardation, hearing and loss of vision.

Clinical symptoms, particularly ocular toxoplasmosis, can also occur in otherwise healthy adults but serious disease and death is more often associated with immunosuppressed individuals. Even though a small percentage of people infected with T.